acute toxicity studies of syzygium guineenses

acute toxicity studies of syzygium guineenses

TOXICITY OF ERYTHROPHLEUM GUINEENSE STEM-BARK: ROLE …

Syzygium guineense is one of such medicinal plants in use. It is traditionally used as a remedy for diarrhea, stomach pain and intestinal cramps. The toxic effects of these plants are often not put into considerations when they are being used. In this study we attempted to investigate the toxic effect of Syzygium guineense. On the histopathology of the liver of mice we choose the Liver because ...

International Journal of Research in Pharmacology and ...

The phytochemical, antimicrobial and acute toxicity studies of the leaf and stem bark extracts of Syzygium cumini Linn. grown in Abuja, Nigeria was carried out.

Effect of Aqueous Extract of Piper Guineense Seeds on Some ...

The phytochemical, antimicrobial and acute toxicity studies of the leaf and stem bark extracts of Syzygium cumini Linn. grown in Abuja, Nigeria was carried out. The phytochemical screening revealed the presence of carbohydrates, saponins, tannins, terpenes, volatile oil, sterols, resins balsam, phlobatanins and flavonoids in the leaves and stem ...

Antimalarial activity of Syzygium guineense during early ...

Materials and Methods: Acute toxicity tests were conducted by the oral administration of 250, 500, and 1,000 mg/kg body weight of the animal. In chronic study, animals were administered with various doses of asafetida (25, 50, 100, and 200 mg/kg body weight) for a period of 6 weeks.

3- SYZYGIUM CUMINI (L.) SKEELS A REVIEW OF ITS ...

ACUTEDefinition - Acute dermal toxicity - dose The adverse effects occurring within a short time of dermal application of a single d...

THE PRELIMINARY PHYTOCHEMICAL ANALYSIS AND ORAL ACUTE ...

This study examines the effects of a methanol extract of Syzygium guineense leaves in streptozotocin (STZ) - induced diabetes, evaluates its effect on alpha glucosidase and 2, …

Preliminary Phytochemical, Antimicrobial and Acute ...

Acute toxicity study The acute toxicity of Ethanol extracts of Syzygium alternifolium fruit was determined as per the OECD guideline no. 423 (Acute Toxic Class Method). It was observed that the test extract was not lethal to the rats even at 2000mg/kg 2000mg/kg doses. Hence, 1 ...

In vivo toxicity evaluation of a standardized extract of ...

Acute toxicity study The safety of the extract when taken acutely was performed according to the OECD guideline 425. A fixed dose of 2000 mg/kg body weight of S. guineense crude leaf extract was administered to a single mouse via the oral route by gavage.

Hemorrhagic Centrolobar Necrosis and Cytoplasmic ...

Ugbabe et al. (2010) used 70% methanolic extract for acute toxicity studies in mice using the the leaves and stem bark of S. cumini . Nine mice were divided into three groups of three each for the phase I study.

Preliminary phytochemical, antimicrobial and acute ...

Acute toxicity study The safety of the extract when taken acutely was performed according to the OECD guideline 425. A fixed dose of 2000 mg/kg body weight of S. guineense crude leaf extract was administered to a single mouse via the oral route by gavage.

The toxicity evaluation of Syzygium cumini Brazilian ...

Evaluation of acute and sub-acute safety profile of ...

THE PRELIMINARY PHYTOCHEMICAL ANALYSIS AND ORAL ACUTE ...

2011-04-12· AIM OF THE STUDY: Acute and subchronic oral toxicity studies of Nelumbo nucifera stamens extract in rats were performed in the present study in order to evaluate its safety. MATERIALS AND METHODS: In acute toxicity study, Nelumbo nucifera stamens extract was administered by oral gavage to Sprague-Dawley rats (5 males and 5 females) at a dose of 5000 mg/kg. In subchronic toxicity study…

In vivo toxicity evaluation of a standardized extract of ...

Acute toxicity studies of syzygium guineenses Products. As a leading global manufacturer of crushing, grinding and mining equipments, we offer advanced, reasonable solutions for any size-reduction requirements including, Acute toxicity studies of syzygium guineenses, quarry, aggregate, and different kinds of minerals.

Acute Toxicity2 | Toxicity | Dose (Biochemistry)

anti-venom studies on olax viridis and syzygium guineense extracts. Apr 12, 2013 ... Syzygium guineense has been reported as antidiarrheal agent. .... animals were used as approved in the study of snake venom toxicity.

Evaluation of acute and sub-acute safety profile of ...

S. guineense is a leafy forest tree found in many parts of Africa both wild and domesticated. S. guineense is the most wide spread and abundant Syzygium in Nigeria.

Antimalarial activity of Syzygium guineense during early ...

The present study is therefore aimed at investigating the effect of aqueous extract of Piper guineense seeds on some liver enzymes, antioxidant enzymes and some hematological

Antidiabetic potentials of Syzygium guineense methanol ...

the preliminary phytochemical analysis and oral acute toxicity study of stem bark of syzygium cumini Objective: The current subject field was carried out to evaluate phytochemical analysis and acute toxicity study of the stem bark of Syzygium cumini .

Anti-Inflammatory and Analgesic Activities of the ...

This study found evidence to suggest that, based on the interpretation of the analyzed parameters, the hydroalcoholic extract of Syzygium cumini does not produce acute toxic and/or chronic effect when administered orally, but does present acute toxicity when administered via intraperitoneal route.

Acute toxicity studies of syzygium guineenses - okdgroup.in

In this study, the acute and subchronic toxicity effect of the Syzygium aqueum leaf extract (SA) was evaluated. For the acute toxicity study, a single dose of 2000mg/kg of the SA was givenbyoral-gavagetomaleSprague-Dawley(SD)rats.Theratswereobservedformortal-ity and toxicity signs for 14 days. In the subchronic toxicity study the SA was administered orally at doses of 50, 100, and 200mg/kg …

Evaluation of Toxicity Effects of Asafetida on Biochemical ...

guineense in imparting acute toxicity, discouraging oviposition and damage to bambarra groundnut seeds by C. subinnotatus has been demonstrated in this study.

The toxicity evaluation of Syzygium cumini leaves in rodents

In this study, the acute and subchronic toxicity effect of the Syzygium aqueum leaf extract (SA) was evaluated. For the acute toxicity study, a single dose of 2000 mg/kg of the SA was given by oral-gavage to male Sprague-Dawley (SD) rats.

Antimalarial activity of Syzygium guineense during early ...

Syzygium guineense Fruits Sheila Maregesi1, Godeliver Kagashe2, Charles W. Messo3, ... of toxicity. The fruit pulp contains various amounts of macro elements and micro elements. To our understanding, this is the first study on S ...

acute toxicity studies of syzygium guineenses

Conclusion: Syzygium guineense leaf extract possess antimalarial activity in mice. The test substance was found to The test substance was found to be safe with no observable signs of toxicity in the study …

BIOACTIVITY OF TWO POWDERED SPICES [PIPER GUINEENSE …

The toxicity of the stem-bark of E. guineense could be attributed to the combined toxicity of other constituents such as tannins, saponins and glycosides with the alkaloids as earlier speculated.

Determination of Mineral Content, Cytotoxicity and ...

Abstract: This study aimed to evaluate the safety of the hydroalcoholic extract (HE) of Syzygium cumini (L.) Skeels, Myrtaceae, leaves in rodents. Acute toxicity was

Acute and subchronic oral toxicity studies of Nelumbo ...

Syzygium guineense (Myrtaceae) (Wild) DC is a flowering plant found in the wild, native to the wooded savannah and tropical forest of Africa, with characteristics odour and edible fruits [6] .

(PDF) SYZYGIUM CUMINI (L.) SKEELS: A REVIEW OF ITS ...

The results of acute toxicity study of stem bark of Syzygium cumini showed no noticeable signs of acute toxicity and mortality was not noticed at any dose up to 5000 mg/kg body weight.

ISSN (E): 2277- 7695 ISSN (P): 2349-8242 Evaluation of ...

In the study of anti-dia betic pote ntial of S. cumini by Deb et al. (2013), acute toxicity study of methanolic and aqueous e xtracts of l eaves, seeds, barks, and r oots was conducted in albino ...